A
lot of scintists believe that one of main reasons for cellular
senecsence is oxidative stress. Active forms of oxigen, like hydroxyl
ion or single oxygen, could appear in the cell during mitochondria's
work and as side product of a lot of other cellular processes. If you
want to read more, just read a book....
There
are also organels in cell that can utilize active forms of oxygen.
These organels are called peroxisomes, they containe enzymes able to
convert active forms of oxigen into safe O2 and water. Scientist
from University
of Basel, Switzerland managed to create artificial peroxisomes,a
polymeric capsules with channels which allow chemicals and compounds
to get in and out of the peroxisome.
Artifical
peroxisomes successfuly helped to utilize active forms of oxygen and
they could effectivly prevent cellular senescense.
Aiding Nature’s Organelles: Artificial Peroxisomes Play Their Role
Department of
Chemistry, University of Basel, Klingelbergstrasse 80, CH-4056
Basel, Switzerland
Nano
Lett., 2013, 13 (6),
pp 2875–2883, DOI: 10.1021/nl401215n
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